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Amitriptyline is in a class of drugs called tricyclic antidepressants. Amitriptyline affects chemicals in your brain that may become unbalanced and cause depression.

Amitriptyline is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide. Amitriptyline is also sometimes used to treat certain types of pain.

It may be 4 weeks or more before you start to feel better, but do not stop taking amitriptyline without first talking to your doctor.

Use caution when driving, operating machinery, or performing other hazardous activities. Amitriptyline may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.

Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking amitriptyline.